Lacto-N-neotetraose CAS 13007-32-4

1. Lacto-N-neotetraose is a key human milk oligosaccharide (HMO) and the third most abundant solid component in breast milk, widely used as a functional ingredient in infant formula and nutritional supplements to support the development of a healthy gut microbiota in newborns .
2. Lacto-N-neotetraose CAS 13007-32-4 functions as a prebiotic that selectively promotes the growth of beneficial *Bifidobacterium* species in the infant gut and exhibits anti-adhesive properties by serving as a soluble receptor decoy, preventing the attachment of pathogenic bacteria to the intestinal lining .
3. Lacto-N-neotetraose has demonstrated anti-inflammatory activity by inhibiting TNF- induced IL-8 secretion in immature epithelial cells, with research showing Lacto-N-neotetraose CAS 13007-32-4 can bind to tumor necrosis factor receptor 1 (TNFR1) and reduce inflammation through receptor shedding mechanisms .
4. In research applications, Lacto-N-neotetraose is utilized as a model oligosaccharide for studying microbial biosynthesis pathways, with recent engineering advances achieving production titers exceeding 30 g/L in microbial fermentation systems using engineered *E. coli* and *Corynebacterium glutamicum* .

1. Lacto-N-neotetraose must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment at 2-8℃ (refrigerated), protected from light and moisture to maintain stability and prevent degradation .
2. For long-term stability, Lacto-N-neotetraose powder can be stored at -20℃ for extended periods, while stock solutions should be prepared in aliquots and stored at -20℃ for up to 1 month, avoiding repeated freeze-thaw cycles to prevent potency loss .
3. Personnel Lacto-N-neotetraose CAS 13007-32-4 must wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling Lacto-N-neotetraose, as Lacto-N-neotetraose CAS 13007-32-4 may cause mild skin, eye, and respiratory tract irritation .
4. Lacto-N-neotetraose is hygroscopic and should be stored in a tightly sealed container away from incompatible materials such as strong oxidizing agents; the product is stable for up to 3 years when stored under recommended conditions .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable dust respirator when Lacto-N-neotetraose is released .
2. Collect Lacto-N-neotetraose CAS 13007-32-4 by sweeping or vacuuming without creating dust using non-sparking tools, and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure; decontaminate surfaces using appropriate methods, and prevent Lacto-N-neotetraose from entering drains or water courses .
4. Dispose of collected material according to local, state, and federal environmental regulations; Lacto-N-neotetraose is considered non-hazardous for transport under normal conditions .

1. Lacto-N-neotetraose is not classified as highly flammable (flash point 663.6±34.3℃) but is a combustible solid that may decompose under fire conditions, emitting toxic fumes including carbon monoxide and carbon dioxide .
2. Use water spray, dry chemical powder, carbon dioxide, or alcohol-resistant foam to extinguish fires involving the product; do NOT use a direct water jet as Lacto-N-neotetraose CAS 13007-32-4 may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning Lacto-N-neotetraose due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, Lacto-N-neotetraose may emit irritant and toxic fumes; contain fire runoff to prevent environmental contamination and avoid release into waterways .